Modular development of organelle-targeting fluorescent probes for imaging formaldehyde in live cells

Author:

Zhang Yuqing1,Du Yimeng1,Liao Kongke1,Peng Tao12ORCID

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China

2. Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518132, China

Abstract

A modular strategy is developed to construct diverse organelle-targeting fluorescent probes for selective imaging of formaldehyde in the nucleus, ER, mitochondria, and lysosomes of live cells.

Funder

National Natural Science Foundation of China

Science, Technology and Innovation Commission of Shenzhen Municipality

Shenzhen-Hong Kong Institute of Brain Science

Publisher

Royal Society of Chemistry (RSC)

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