Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy-Reference-Cited by-同舟云学术

Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy

Published:2017 Issue:4 Volume:2 Page:531-540
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Aßmann M.¹²³⁴,Stöbener A.¹²³⁴,Mügge C.⁵⁶⁷⁴^ORCID,Gaßmeyer S. K.⁵⁶⁷⁴,Hilterhaus L.¹²³⁴,Kourist R.⁵⁶⁷⁴⁸,Liese A.¹²³⁴^ORCID,Kara S.¹²³⁴^ORCID

Affiliation:

1. Institute of Technical Biocatalysis

2. Hamburg University of Technology

3. 21073 Hamburg

4. Germany

5. Junior Research Group for Microbial Biotechnology

6. Ruhr-University Bochum

7. 44780 Bochum

8. Institute of Molecular Biotechnology

Abstract

Biocatalytic (S)-naproxen synthesis using an (S)-selective arylmalonate decarboxylase mutant (AMDase G74C/M159L/C188G/V43I/A125P/V156L, AMDase-CLGIPL) exposes a promising environmentally friendly alternative to conventional chemical synthesis strategies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RE/C7RE00043J

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