Pyruvic acid or DBU/O2 guided organophotoredox-catalyzed direct C–H alkylation/α-aminoalkylation of 1,2,4-triazine-3,5(2H,4H)-diones with amines-Reference-Cited by-同舟云学术

Pyruvic acid or DBU/O₂ guided organophotoredox-catalyzed direct C–H alkylation/α-aminoalkylation of 1,2,4-triazine-3,5(2H,4H)-diones with amines

Published:2024 Issue: Volume: Page:
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Cai Zhao-Nan¹,Cao Xiaohui²^ORCID,Zhang Hong-Yu¹^ORCID,Zhang Yuecheng¹^ORCID,Zhao Jiquan¹^ORCID

Affiliation:

1. School of Chemical Engineering and Technology, Hebei Provincial Key Lab of Green Chemical Technology & High Efficient Energy Saving, Tianjin Key Laboratory of Chemical Process Safety, Hebei University of Technology, Tianjin 300401, P. R. China

2. School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China

Abstract

Herein, we present an organophotoredox-catalyzed direct C–H alkylation/α-aminoalkylation of 1,2,4-triazine-3,5(2H,4H)-diones with amines in the presence of different additives. In addition, reaction mechanism were further revealed via DFT studies.

Funder

Natural Science Foundation of Hebei Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO01175A

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