Enantioselective synthesis of functionalized 1,4-dihydropyrazolo-[4′,3′:5,6]pyrano[2,3-b]quinolines through ferrocenyl-phosphine-catalyzed annulation of modified MBH carbonates and pyrazolones

Author:

Xiao Xiao12345,Shao Bingxuan5234,Li Jingyi5234,Yang Zehui5234ORCID,Lu Yin-Jie1234,Ling Fei5234ORCID,Zhong Weihui5234ORCID

Affiliation:

1. Institute of Pharmaceutical Science and Technology

2. Zhejiang University of Technology

3. Hangzhou 310014

4. People's Republic of China

5. College of Pharmaceutical Sciences

Abstract

An enantioselective synthesis of 1,4-dihydropyrazolo[4′,3′:5,6]pyrano[2,3-b]quinolines from modified MBH carbonates and pyrazolones via a chiral phosphine-mediated alkylation/annulation sequence has been realized.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference57 articles.

1. J. Elguero , in Comprehensive Heterocyclic Chemistry , ed. A. R. Katritzky and Rees, C. W. , Pergamon Press , Oxford, U.K. , 1984 , Vol. 5, p. 167

2. J. Elguero , in Comprehensive Heterocyclic Chemistry II , ed. A. R. Katritzky , C. W. Rees and E. F. V. Scriven , Pergamon Press , Oxford, U.K. , 1996 , Vol. 3, p. 1

3. B. Stanovnik and J.Svete , Pyrazoles , in Science of Synthesis: Houben-Weyl Methods of Organic Transformations , ed. R. Neier , Georg Thieme , Stuttgart, Germany , 2002 , Vol. 12, p. 15

4. L. Yet , in Comprehensive Heterocyclic Chemistry III , ed. A. R. Katritzky , C. A. Ramsden , E. F. V. Scriven , and R. J. K. Taylor , Elsevier , Oxford, U.K. , 2008 , Vol. 4, p. 1

5. G. Varvounis , Pyrazol-3-ones. Part IV , in Synthesis and Applications”: in Advances in Heterocyclic Chemistry , ed. A. R. Katritzky , Academic Press , New York , 2009 , Vol. 98, p. 143

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