Preparation of zwitterionic random and block poly(<i>N</i>-α-acrylamide-<scp>l</scp>-lysine-<i>co</i>-2-methacryloyloxyethyl phosphorylcholine) copolymers and their effect on fibrinolytic activity-Reference-Cited by-同舟云学术

Preparation of zwitterionic random and block poly(N-α-acrylamide-l-lysine-co-2-methacryloyloxyethyl phosphorylcholine) copolymers and their effect on fibrinolytic activity

Published:2024 Issue:11 Volume:5 Page:4818-4831
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Nakago Tomoya¹^ORCID,Oki Yuto¹,Nousou Tatsuki¹^ORCID,Ogawa Tomohiro²,Shiraishi Kohei¹³⁴^ORCID

Affiliation:

1. Major in Systems Engineering, Graduate School of Systems Engineering, Kindai University, 1 Umenobe, Takaya, Higashihiroshima, Hiroshima 739-2116, Japan

2. Center for the Advancement of Higher Education, Faculty of Engineering, Kindai University, 1 Umenobe, Takaya, Higashihiroshima, Hiroshima 739-2116, Japan

3. Department of Biotechnology and Chemistry, Faculty of Engineering, Kindai University, 1 Umenobe, Takaya, Higashihiroshima, Hiroshima 739-2116, Japan

4. Research Institute of Fundamental Technology for Next Generation, Kindai University, 1 Umenobe, Takaya, Higashihiroshima, Hiroshima 739-2116, Japan

Abstract

We have developed N-α-lysine acrylamide (LysAA) with a lysine side chain that enhances the fibrinolytic system; random copolymerization of LysAA with MPC [20% molar ratio] enhanced the fibrinolytic activity of LysAA.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MA/D4MA00267A

Reference26 articles.

1. New insights into the molecular mechanisms of the fibrinolytic system

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5. Preparation of poly(methyl methacrylate) microspheres modified with amino acid moieties