Reactivity of steroidal 1-azadienes toward enamines: an approach to novel chiral penta- and hexacyclic steroids-Reference-Cited by-同舟云学术

Reactivity of steroidal 1-azadienes toward enamines: an approach to novel chiral penta- and hexacyclic steroids

Published:2021 Issue:5 Volume:19 Page:1122-1132
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lopes Susana M. M.¹²³⁴^ORCID,Santos Joana R. C.¹²³⁴^ORCID,Pinho e Melo Teresa M. V. D.¹²³⁴^ORCID

Affiliation:

1. University of Coimbra

2. Coimbra Chemistry Centre and Department of Chemistry

3. 3004-535 Coimbra

4. Portugal

Abstract

Steroidal 1-azadienes react with cyclic ketones to afford hexacyclic steroids via annulation reaction while the reaction with aldehydes gives pentacyclic steroids via hetero-Diels–Alder reactions.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02344B

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