Interrogating bioinspired ESIPT/PCET-based Ir(<scp>iii</scp>)-complexes as organelle-targeted phototherapeutics: a redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis-Reference-Cited by-同舟云学术

Interrogating bioinspired ESIPT/PCET-based Ir(iii)-complexes as organelle-targeted phototherapeutics: a redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis

Published:2023 Issue:36 Volume:14 Page:9872-9884
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Shee Maniklal¹,Zhang Dan²,Banerjee Moumita¹,Roy Samrat³,Pal Bipul³^ORCID,Anoop Anakuthil¹^ORCID,Yuan Youyong²^ORCID,Singh N. D. Pradeep¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology, Kharagpur, West Bengal–721302, India

2. School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou International Campus, Guangzhou 511442, PR China

3. Department of Physics, Indian Institute of Science Education and Research Kolkata, Mohanpur, West Bengal 741246, India

Abstract

We investigated organelle-targeted bioinspired ESIPT/PCET-based Ir(iii)-complexes as promising (photo)chemotherapeutic lead compounds which actively operational in redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis.

Funder

Science and Engineering Research Board

National Key Research and Development Program of China

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03096B

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