Effect of substituents and chain length in amino-1,4-naphthoquinones on glutathione-S-transferase inhibition: molecular docking and electrochemical perspectives: a structure

Effect of substituents and chain length in amino-1,4-naphthoquinones on glutathione-S-transferase inhibition: molecular docking and electrochemical perspectives: a structure–activity study

Published:2022 Issue:45 Volume:46 Page:21648-21659
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Faúndes Judith¹^ORCID,Muñoz-Osses Michelle¹^ORCID,Morales Pilar¹,Tasca Federico²^ORCID,Loyola César Zúñiga²^ORCID,Faúndez Mario³,Mascayano Carolina¹^ORCID,Ibacache Juana A.¹

Affiliation:

1. Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Casilla 40, Correo 33, Sucursal Matucana, Santiago, 9170022, Chile

2. Departamento de Química de Los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile, Casilla 40, Correo 33, Sucursal Matucana, Santiago, 9170022, Chile

3. Pontificia Universidad Católica de Chile, Facultad de Química, Departamento de Farmacia, Laboratorio de Toxicología, Vicuña Mackenna 4860, 7820436, Macul, Santiago, Chile

Abstract

The highlights of structure–activity relationship in GST inhibition.

Funder

Departamento de Investigaciones Científicas y Tecnológicas, Universidad de Santiago de Chile

Fondo Nacional de Desarrollo Científico y Tecnológico

Agencia Nacional de Investigación y Desarrollo

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ04079D

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