From discovery to scale-up: α-lipoic acid : nicotinamide co-crystals in a continuous oscillatory baffled crystalliser-Reference-Cited by-同舟云学术

From discovery to scale-up: α-lipoic acid : nicotinamide co-crystals in a continuous oscillatory baffled crystalliser

Published:2014 Issue:26 Volume:16 Page:5769-5780
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Zhao Lihua¹²³,Raval Vishal¹²³,Briggs Naomi E. B.¹²³,Bhardwaj Rajni M.⁴²⁵,McGlone Thomas¹²³,Oswald Iain D. H.⁴²⁵,Florence Alastair J.¹²³

Affiliation:

1. EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallisation c/o Strathclyde Institute of Pharmacy and Biomedical Sciences

2. University of Strathclyde

3. Glasgow, UK

4. Strathclyde Institute of Pharmacy and Biomedical Sciences

5. , UK

Abstract

Discovery, characterisation and scale-up of novel α-lipoic acid co-crystals using continuous crystallisation in a COBC is demonstrated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CE/C4CE00154K

Reference90 articles.

1. Receptor site and stereospecifity of dihydrolipoamide dehydrogenase for R- and S-lipoamide: a molecular modeling study

2. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis

3. Oral Treatment With α-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy

4. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease☆

5. The antioxidant effect of DL-α-lipoic acid on copper-induced acute hepatitis in Long-Evans Cinnamon (LEC) rats

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