DBU-catalyzed dearomative annulation of 2-pyridylacetates with α,β-unsaturated pyrazolamides for the synthesis of multisubstituted 2,3-dihydro-4H-quinolizin-4-ones-Reference-Cited by-同舟云学术

DBU-catalyzed dearomative annulation of 2-pyridylacetates with α,β-unsaturated pyrazolamides for the synthesis of multisubstituted 2,3-dihydro-4H-quinolizin-4-ones

Published:2022 Issue:1 Volume:9 Page:88-94
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Shen Yao-Bin¹²³,Zhao Jian-Qiang²^ORCID,Wang Zhen-Hua²^ORCID,You Yong²^ORCID,Zhou Ming-Qiang¹,Yuan Wei-Cheng¹²^ORCID

Affiliation:

1. National Engineering Research Center of Chiral Drugs, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China

2. Innovation Research Center of Chiral Drugs, Institute for Advanced Study, Chengdu University, Chengdu 610106, China

3. University of Chinese Academy of Sciences, Beijing, 100049, China

Abstract

DBU-catalyzed dearomative [3 + 3] annulation of 2-pyridylacetates and α,β-unsaturated pyrazolamides for the synthesis of multisubstituted 2,3-dihydro-4H-quinolizin-4-ones was developed.

Funder

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Chengdu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01414E

Reference63 articles.

1. Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics