In situ differentiation and generation of functional liver organoids from human iPSCs in a 3D perfusable chip system
Author:
Affiliation:
1. Division of Biotechnology
2. CAS Key Laboratory of Separation Sciences for Analytical Chemistry
3. Dalian Institute of Chemical Physics
4. Chinese Academy of Sciences
5. Dalian 116023
Abstract
We present a new strategy to engineer human iPSC-derived liver organoids by combining stem cell biology with a microfluidic chip system.
Funder
Chinese Academy of Sciences
National Natural Science Foundation of China
Dalian Institute of Chemical Physics
Publisher
Royal Society of Chemistry (RSC)
Subject
Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering
Link
http://pubs.rsc.org/en/content/articlepdf/2018/LC/C8LC00869H
Reference40 articles.
1. The promise of induced pluripotent stem cells in research and therapy
2. Human induced pluripotent stem cells and their use in drug discovery for toxicity testing
3. iPS cells: a game changer for future medicine
4. Potential of human induced pluripotent stem cells in studies of liver disease
5. Next-Generation Regenerative Medicine: Organogenesis from Stem Cells in 3D Culture
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