Apoptotic mechanisms of gastric cancer cells induced by isolated erinacine S through epigenetic histone H3 methylation of FasL and TRAIL

Author:

Tung Shui-Yi12345,Lee Ko-Chao67285,Lee Kam-Fai9234,Yang Ya-Ling1011124,Huang Wen-Shih5134147,Lee Li-Ya15164,Chen Wan-Ping15164,Chen Chin-Chu15164ORCID,Teng Chih-Chuan17181934,Shen Chien-Heng1234,Hsieh Meng-Chiao147234,Huang Cheng-Yi147234,Sheen Jiunn-Ming202134,Kuo Hsing-Chun17181934ORCID

Affiliation:

1. Department of Hepato-Gastroenterology

2. Chang Gung Memorial Hospital

3. Chiayi

4. Taiwan

5. Chang Gung University College of Medicine

6. Division of Colorectal Surgery

7. Department of Surgery

8. Kaohsiung Medical Center

9. Department of Pathology

10. Department of Anesthesiology

11. Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine

12. Kaohsiung

13. Taoyuan

14. Division of Colon and Rectal Surgery

15. Grape King Biotechnology Inc. (Grape King Bio Ltd)

16. Zhong-Li

17. Department of Nursing

18. Division of Basic Medical Sciences

19. Chang Gung University of Science and Technology

20. Department of Pediatrics

21. Chiayi Chang Gung Memorial Hospital and Chang Gung University College of Medicine

Abstract

Erinacine S, the new bioactive diterpenoid compound isolated from the ethanol extract of the mycelia of Hericium erinaceus, displays great health-promoting properties.

Funder

Ministry of Science and Technology, Taiwan

Chiayi Chang Gung Memorial Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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