Charged chiral derivatization for enantioselective imaging of <scp>d-,l</scp>-2-hydroxyglutaric acid using ion mobility spectrometry/mass spectrometry-Reference-Cited by-同舟云学术

Charged chiral derivatization for enantioselective imaging of d-,l-2-hydroxyglutaric acid using ion mobility spectrometry/mass spectrometry

Published:2023 Issue:73 Volume:59 Page:10916-10919
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Sugiyama Eiji¹^ORCID,Nishiya Yuki¹,Yamashita Kenji¹,Hirokawa Ryo¹,Iinuma Yoshiteru²,Nirasawa Takashi³,Mizuno Hajime¹⁴,Hamashima Yoshitaka¹^ORCID,Todoroki Kenichiro¹^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan

2. Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Kunigami-gun, Okinawa, 904-0495, Japan

3. Daltonics Division, Bruker Japan K.K., Moriyacho Kanagawa-ku, Yokohama-shi, Kanagawa 221-0022, Japan

4. Laboratory of Analytical Chemistry, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya, 468-8503, Japan

Abstract

A newly synthesized charged chiral tag-enabled enantioselective imaging of d- and l-2-hydroxyglutaric acid, which are independently associated with the regulation of DNA methylation, using MALDI/ion mobility spectrometry/mass spectrometry.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01963B

Reference22 articles.

1. Chiral monoterpenes reveal forest emission mechanisms and drought responses

2. Simultaneous determination of all aminobutyric acids by chiral derivatization and liquid chromatography-tandem mass spectrometry

3. Enantioseparation of d,l-2-hydroxyglutaric acid by capillary electrophoresis with tandem mass spectrometry—Fast and efficient tool for d- and l-2-hydroxyglutaracidurias diagnosis

4. Dried Saliva Spot (DSS) as a Convenient and Reliable Sampling for Bioanalysis: An Application for the Diagnosis of Diabetes Mellitus

5. Three-Dimensional High-Performance Liquid Chromatographic Determination of Asn, Ser, Ala, and Pro Enantiomers in the Plasma of Patients with Chronic Kidney Disease

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