In vitro to in vivo extrapolation to support the development of the next generation risk assessment (NGRA) strategy for nanomaterials

Author:

Jagiello Karolina12ORCID,Ciura Krzesimir13

Affiliation:

1. QSAR Lab Ltd., Trzy Lipy 3, 80-172 Gdansk, Poland

2. University of Gdansk, Faculty of Chemistry, Wita Stwosza 63, 80-308 Gdansk, Poland

3. Medical University of Gdansk, Faculty of Pharmacy, Department of Physical Chemistry, J. Hallera Avenue 107, 80-416, Gdansk, Poland

Abstract

The in vitro to in vivo extrapolation models (IVIVE) can support the development of the Next Generation Risk Assessment through integration the AOP-anchored strategy for in vitro assays selection with the PBPK models.

Funder

H2020 Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Reference43 articles.

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