Oligonol ameliorates liver function and brain function in the 5 × FAD mouse model: transcriptional and cellular analysis-Reference-Cited by-全球学者库

Oligonol ameliorates liver function and brain function in the 5 × FAD mouse model: transcriptional and cellular analysis

Published:2023 Issue:21 Volume:14 Page:9650-9670
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jo Danbi¹²,Arjunan Archana¹,Choi Seoyoon¹²,Jung Yoon Seok¹,Park Jihyun³⁴,Jo Jihoon⁵,Kim Oh Yoen³⁴,Song Juhyun¹²^ORCID

Affiliation:

1. Department of Anatomy, Chonnam National University Medical School, Seoyangro 264, Hwasun 58128, Republic of Korea

2. Biomedical Science Graduate Program (BMSGP), Chonnam National University, Seoyangro 264, Hwasun 58128, Republic of Korea

3. Department of Food Science and Nutrition, Dong-A University, Nakdong-daero 550 beon-gil, Saha-gu, Busan, 49315, Republic of Korea

4. Department of Health Sciences, Graduate School of Dong-A University, Nakdong-daero 550 beon-gil, Saha-gu, Busan, 49315, Republic of Korea

5. Department of Biomedical Science, Chonnam National University Medical School, Seoyangro 264, Hwasun 58128, Republic of Korea

Abstract

5 × FAD Alzheimer's disease male mice were treated orally with oligonol at a daily dose of 50 mg kg−1 for 8 weeks. Oligonol oral treatment was found to improve cognitive function, and to reduce anxiety and depression in 5 × FAD Alzheimer's disease mouse.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO03451H

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