Enabling synthesis in fragment-based drug discovery (FBDD): microscale high-throughput optimisation of the medicinal chemist's toolbox reactions-Reference-Cited by-同舟云学术

Enabling synthesis in fragment-based drug discovery (FBDD): microscale high-throughput optimisation of the medicinal chemist's toolbox reactions

Published:2023 Issue:12 Volume:14 Page:2699-2713
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Townley Chloe¹,Branduardi Davide¹,Chessari Gianni¹^ORCID,Cons Benjamin D.¹^ORCID,Griffiths-Jones Charlotte¹,Hall Richard J.¹^ORCID,Johnson Christopher N.¹^ORCID,Ochi Yuji¹,Whibley Stuart¹,Grainger Rachel¹^ORCID

Affiliation:

1. Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge, CB4 0QA, UK

Abstract

Democratised high-throughput experimentation for FBDD.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00495C

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5. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

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