Endometriosis-targeted MRI imaging using bevacizumab-modified nanoparticles aimed at vascular endothelial growth factor-Reference-Cited by-同舟云学术

Endometriosis-targeted MRI imaging using bevacizumab-modified nanoparticles aimed at vascular endothelial growth factor

Published:2023 Issue:15 Volume:5 Page:3994-4001
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Zhang Qi¹,Wu Shiman¹,Li Yajie¹,Lai Mao²,Li Qing³,Fu Caixia⁴,Yao Zhenwei¹,Zhang Junhai¹^ORCID

Affiliation:

1. Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, P.R. China

2. Department of Radiology, The First People's Hospital of Jinghong, Jinghong City, Yunnan Province, P.R. China

3. MR Collaborations, Siemens Healthineers Digital Technology (Shanghai) Co., Ltd, Shanghai, China

4. MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd, Gaoxin C. Ave, 2nd, Hi-Tech Industrial Park, Shenzhen, 518057, China

Abstract

By targeting the enriched vascular endothelial growth factor receptor (VEGFR) in endometriosis, we develop an MRI contrast agent, NaGdF4@PEG@bevacizumab–Cy5.5 nanoparticles (NPBCNs) to detect endometriosis in MRI and fluorescence imaging.

Funder

National Natural Science Foundation of China

Shanghai Municipal Health Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NA/D2NA00787H

Reference28 articles.

1. Endometriosis

2. Pelvic endometriosis and natural killer cell immunity

3. Creating Solutions in Endometriosis: Global Collaboration through the World Endometriosis Research Foundation

4. Endometrial epithelial cells-derived exosomes deliver microRNA-30c to block the BCL9/Wnt/CD44 signaling and inhibit cell invasion and migration in ovarian endometriosis

5. Incidence of Laparoscopically Confirmed Endometriosis by Demographic, Anthropometric, and Lifestyle Factors

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