A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones-Reference-Cited by-同舟云学术

A continuing challenge: N-heterocyclic carbene-catalyzed syntheses of γ-butyrolactones

Published:2018 Issue:5 Volume:47 Page:1773-1782
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Murauski Kathleen J. R.¹²³⁴⁵,Jaworski Ashley A.¹²³⁴⁵,Scheidt Karl A.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Department of Pharmacology

3. Center for Molecular Innovation and Drug Discovery

4. Northwestern University

5. Evanston

Abstract

Catalytic, stereoselective N-heterocyclic carbene-catalyzed reactions facilitate efficient construction of many different heterocyclic compounds, such as the enantioenriched 5-membered (γ) lactones highlighted in this tutorial review.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CS/C7CS00386B

Reference50 articles.

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2. Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

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4. An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

5. Conjugate Umpolung of β,β-Disubstituted Enals by Dual Catalysis with an N-Heterocyclic Carbene and a Brønsted Acid: Facile Construction of Contiguous Quaternary Stereocenters

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