Antimicrobial polysiloxane polymers and coatings containing pendant levofloxacin

Author:

Kugel Alex1234,Chisholm Bret12345,Ebert Scott5234,Jepperson Michael5234,Jarabek Laura5234,Stafslien Shane5234

Affiliation:

1. Department of Coatings and Polymeric Materials

2. North Dakota State University

3. Fargo

4. USA

5. Center for Nanoscale Science and Engineering

Abstract

A siloxane copolymer with covalently attached levofloxacin was synthesized. Crosslinked coatings made from the siloxane copolymer displayed a uniform drug distribution, higher initial kill, and sustained antimicrobial surface activity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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