An amplification-free ultra-sensitive electrochemical CRISPR/Cas biosensor for drug-resistant bacteria detection-Reference-Cited by-同舟云学术

An amplification-free ultra-sensitive electrochemical CRISPR/Cas biosensor for drug-resistant bacteria detection

Published:2021 Issue:38 Volume:12 Page:12733-12743
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Suea-Ngam Akkapol¹^ORCID,Howes Philip D.¹²^ORCID,deMello Andrew J.¹^ORCID

Affiliation:

1. Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg1, 8093, Zürich, Switzerland

2. Division of Mechanical Engineering and Design, School of Engineering, London South Bank University, 103 Borough Road, London SE1 0AA, UK

Abstract

An amplification-free electrochemical CRISPR/Cas biosensor utilizing silver metallization (termed E-Si-CRISPR) allows detection of methicillin-resistant Staphylococcus aureus (MRSA) with excellent sensitivity and specificity.

Funder

Eidgenössische Technische Hochschule Zürich

Staatssekretariat für Bildung, Forschung und Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC02197D

Reference42 articles.

1. Multiplex Genome Engineering Using CRISPR/Cas Systems

2. CRISPR/Cas Systems towards Next-Generation Biosensing