HIV-1 drug discovery: targeting folded RNA structures with branched peptides

Author:

Wynn Jessica E.1234,Santos Webster L.1234

Affiliation:

1. Department of Chemistry and Virginia Tech Center for Drug Discovery

2. Virginia Tech

3. Blacksburg

4. USA

Abstract

Branched peptides utilize multivalent binding to selectively recognize HIV RNA.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference124 articles.

1. A reflection on HIV/AIDS research after 25 years

2. 25 years of HIV-1 research – progress and perspectives

3. UNAIDS, Regional HIV and AIDS statistics, 2001 and 2009, http://www.unaids.org/documents/20101123_globalreport_slides_chapter2_em.pdf

4. The causes and consequences of HIV evolution

5. Newly identified host factors modulate HIV replication

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