Nucleic acid constructs for the interrogation of multivalent protein interactions-Reference-Cited by-同舟云学术

Nucleic acid constructs for the interrogation of multivalent protein interactions

Published:2020 Issue:19 Volume:49 Page:6848-6865
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Yeldell Sean B.¹²³⁴⁵,Seitz Oliver¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Humboldt-Universität zu Berlin

3. Brook-Taylor-Str. 2

4. 12489 Berlin

5. Germany

Abstract

Sequence-programmed self-assembly provides multivalent nucleic acid–ligand constructs used as tailor-made probes for unravelling and exploiting the mechanisms of multivalency-enhanced interactions on protein receptors.

Funder

H2020 European Research Council

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CS/D0CS00518E

Reference55 articles.

1. Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

2. Multivalency as a Chemical Organization and Action Principle

3. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

4. DNA-guided display of proteins and protein ligands for the interrogation of biology

5. DNA nanotechnology from the test tube to the cell

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