Co-delivery of vitamin D3 and Lkb1 siRNA by cationic lipid-assisted PEG-PLGA nanoparticles to effectively remodel the immune system <i>in vivo</i>-Reference-Cited by-同舟云学术

Co-delivery of vitamin D3 and Lkb1 siRNA by cationic lipid-assisted PEG-PLGA nanoparticles to effectively remodel the immune system in vivo

Published:2023 Issue:17 Volume:11 Page:5931-5941
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Liu Haochuan¹²^ORCID,Zhang Yuning¹³⁴,Li He¹⁴,Gao Xue¹,Wang Jialiang¹⁴,Cong Xiuxiu¹⁴,Xin Yanbao¹⁴,Zhu Qingsan²^ORCID,Chen Bing⁵,Yang Yong-Guang¹³⁴,Sun Tianmeng¹³⁴⁶^ORCID

Affiliation:

1. Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, Jilin University, Changchun, Jilin, 130061, China

2. Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130031, China

3. International Center of Future Science, Jilin University, Changchun, Jilin, 130015, China

4. National-local Joint Engineering Laboratory of Animal Models for Human Diseases, Changchun, Jilin, 130062, China

5. Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, 130031, China

6. State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, Jilin, 130012, China

Abstract

Cationic lipid-assisted PEG-PLGA nanoparticles regulate the immune balance by inducing tolerogenic dendritic cells and amplifying regulatory T cells.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

First Hospital of Jilin University

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D3BM00767G

Reference52 articles.

1. ENCEPHALOMYELITIS ACCOMPANIED BY MYELIN DESTRUCTION EXPERIMENTALLY PRODUCED IN MONKEYS

2. Dendritic cell migration in health and disease

3. Tolerogenic dendritic cells and their potential applications

4. Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications

5. Cell-Based Modulation of Autoimmune Responses in Multiple Sclerosis and Experimental Autoimmmune Encephalomyelitis: Therapeutic Implications

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