Evaluation of histone deacetylase inhibitor substituted zinc and indium phthalocyanines for chemo- and photodynamic therapy

Author:

Aru Başak1,Günay Aysel2,Demirel Gülderen Yanıkkaya1,Gürek Ayşe Gül2ORCID,Atilla Devrim2ORCID

Affiliation:

1. Faculty of Medicine, Immunology Department, Yeditepe University, 34755 Ataşehir, İstanbul, Turkey

2. Department of Chemistry, Gebze Technical University, 41400 Gebze, Kocaeli, Turkey

Abstract

3-Hydroxypyridin-2-thione bearing zinc and indium phthalocyanine derivatives, as photosensitizer agents have been synthesized and evaluated for their anti-cancer efficacy on two breast cancer cell lines, MDA-MB-231 and MCF-7 as well as a human endothelial cell line, HUVEC.

Funder

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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