Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89
Author:
Affiliation:
1. Radiochemistry Service and Cyclotron Operations
2. Cancer Biology and Radiology
3. Wake Forest School of Medicine
4. Winston-Salem
5. USA
6. Lumiphore, Inc.
7. Berkeley
8. Department of Chemistry
9. University of California
Abstract
Octadentate terephthalamide ligands can be easily radiolabeled with 89Zr and are highly stable in vitro. They represent a novel class of bifunctional chelators for 89Zr.
Funder
NSF Office of the Director
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CC/C4CC09256B
Reference22 articles.
1. Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2. 89Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer
3. Monitoring Afatinib Treatment in HER2-Positive Gastric Cancer with 18F-FDG and 89Zr-Trastuzumab PET
4. Annotating MYC status with 89Zr-transferrin imaging
5. Targeting the Internal Epitope of Prostate-Specific Membrane Antigen with 89Zr-7E11 Immuno-PET
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