Tetrahydrofuran amino acid-containing gramicidin S analogues with improved biological profiles-Reference-Cited by-同舟云学术

Tetrahydrofuran amino acid-containing gramicidin S analogues with improved biological profiles

Published:2015 Issue:24 Volume:13 Page:6789-6802
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pal Sudip¹²³⁴,Singh Gajendra⁵⁶²³⁴,Singh Shyam⁷²³⁴,Tripathi Jitendra Kumar⁸²³⁴,Ghosh Jimut Kanti⁸²³⁴,Sinha Sudhir⁷²³⁴,Ampapathi Ravi Sankar⁵⁶²³⁴,Chakraborty Tushar Kanti¹²³⁴⁹

Affiliation:

1. Medicinal and Process Chemistry Division

2. CSIR-Central Drug Research Institute

3. Lucknow-226031

4. India

5. Centre for Nuclear Magnetic Resonance

6. SAIF

7. Biochemistry Division

8. Molecular and Structural Biology Division

9. Department of Organic Chemistry

Abstract

Replacement of thed-Phe-Pro units of GS with novel C₆-Bn-substituted tetrahydrofuran amino acid minimized its cytotoxicity while preserving its antimicrobial activity, with a few analogs showing selective anti-TB activity as well.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00622H

Reference86 articles.

1. Diversity of antimicrobial peptides and their mechanisms of action

2. Antimicrobial peptides of multicellular organisms

3. Cationic host defense (antimicrobial) peptides

4. Novel Therapies Based on Cationic Antimicrobial Peptides

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