Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design programprotobuild-Reference-Cited by-同舟云学术

Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design programprotobuild

Published:2011 Issue:4 Volume:9 Page:1169-1188
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bhurruth-Alcor Yushma,Røst Therese,Jorgensen Michael R.,Kontogiorgis Christos,Skorve Jon,Cooper Robert G.,Sheridan Joseph M.,Hamilton William D. O.,Heal Jonathan R.,Berge Rolf K.,Miller Andrew D.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2011/OB/C0OB00146E

Reference67 articles.

1. METABOLIC SYNDROME

2. Diagnosis, prevention, and intervention for the metabolic syndrome

3. Does the Metabolic Syndrome Improve Identification of Individuals at Risk of Type 2 Diabetes and/or Cardiovascular Disease?

4. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

5. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

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