A copper-catalyzed synthesis of aryloxy-tethered symmetrical 1,2,3-triazoles as potential antifungal agents targeting 14 α-demethylase

Author:

Deshmukh Tejshri R.1234,Khedkar Vijay M.56784,Jadhav Rohit G.19104,Sarkate Aniket P.11234,Sangshetti Jaiprakash N.512134ORCID,Tiwari Shailee V.514154,Shingate Bapurao B.1234ORCID

Affiliation:

1. Department of Chemistry

2. Dr. Babasaheb Ambedkar Marathwada University

3. Aurangabad-431004

4. India

5. Department of Pharmaceutical Chemistry

6. School of Pharmacy

7. Vishwakarma University

8. Pune-411048

9. Indian Institute of Technology

10. Indore-453552

11. Department of Chemical Technology

12. Y. B. Chavan College of Pharmacy

13. Aurangabad-431001

14. Durgamata Institute of Pharmacy

15. Dharmapuri, Parbhani-431401

Abstract

The search for potent therapeutic agents has prompted the design and synthesis of a library of twenty-six aryloxy-tethered and amide-linked symmetrical 1,2,3-triazoles (8a–z) using a copper(i)-catalyzed click chemistry approach.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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