DNA damaging, cell cytotoxicity and serum albumin binding efficacy of the rutin

DNA damaging, cell cytotoxicity and serum albumin binding efficacy of the rutin–Cu(ii) complex

Published:2016 Issue:5 Volume:12 Page:1687-1701
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Roy Atanu Singha¹²³⁴,Tripathy Debi Ranjan¹²³⁴,Samanta Sintu⁵²³⁴,Ghosh Sudip K.⁵²³⁴,Dasgupta Swagata¹²³⁴

Affiliation:

1. Department of Chemistry

2. Indian Institute of Technology

3. Kharagpur 721302

4. India

5. Department of Biotechnology

Abstract

The rutin–Cu(ii) complex causes DNA damage and is also able to inhibit the growth of human HeLa cells. This complex binds with serum albuminsviahydrophobic forces.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MB/C6MB00161K

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