One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides-Reference-Cited by-同舟云学术

One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides

Published:2017 Issue:20 Volume:15 Page:4390-4398
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liang Dongdong¹²³⁴^ORCID,Sersen Deanna¹²³⁴^ORCID,Yang Chao⁵⁶⁷⁸⁹^ORCID,Deschamps Jeffrey R.¹⁰¹¹⁴^ORCID,Imler Gregory H.¹⁰¹¹⁴^ORCID,Jiang Chao⁵⁶⁷⁸⁹^ORCID,Xue Fengtian¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences

2. University of Maryland School of Pharmacy

3. Baltimore

4. USA

5. Department of Pharmaceutical Engineering

6. School of Chemical Engineering

7. Nanjing University of Science and Technology

8. Nanjing

9. China

10. Naval Research Laboratory

11. Washington

Abstract

A one-pot synthesis of 2-bromo/chloro-phenanthridinones via an amidation of arenes followed by a regioselective halogenation reaction has been developed using a hypervalent iodine reagent.

Funder

Samuel Waxman Cancer Research Foundation

American Association for Cancer Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00649G

Reference49 articles.

1. Sequential Allylic C–H Amination/Vinylic C–H Arylation: A Strategy for Unnatural Amino Acid Synthesis from α-Olefins

2. Palladium(II)-Catalyzed Sequential C–H Arylation/Aerobic Oxidative C–H Amination: One-Pot Synthesis of Benzimidazole-Fused Phenanthridines from 2-Arylbenzimidazoles and Aryl Halides