Ciprofloxacin intercalated in fluorohectorite clay: identical pure drug activity and toxicity with higher adsorption and controlled release rate-Reference-Cited by-同舟云学术

Ciprofloxacin intercalated in fluorohectorite clay: identical pure drug activity and toxicity with higher adsorption and controlled release rate

Published:2017 Issue:43 Volume:7 Page:26537-26545
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

dos Santos E. C.¹²³⁴⁵^ORCID,Rozynek Z.¹²³⁴⁶^ORCID,Hansen E. L.¹²³⁴^ORCID,Hartmann-Petersen R.⁷⁸⁹¹⁰^ORCID,Klitgaard R. N.⁷⁸⁹¹⁰,Løbner-Olesen A.⁷⁸⁹¹⁰^ORCID,Michels L.¹²³⁴,Mikkelsen A.¹²³⁴⁶^ORCID,Plivelic T. S.¹¹¹²¹³¹⁴^ORCID,Bordallo H. N.⁵⁸⁹¹⁰¹⁵^ORCID,Fossum J. O.¹²³⁴¹⁶^ORCID

Affiliation:

1. Department of Physics

2. Norwegian University of Science and Technology (NTNU)

3. Trondheim

4. Norway

5. Niels Bohr Institute (NBI)

6. Faculty of Physics

7. Department of Biology

8. University of Copenhagen

9. Copenhagen

10. Denmark

11. MAX IV Laboratory

12. Lund University

13. 22100 Lund

14. Sweden

15. European Spallation Source ERIC

16. Institute Pierre-Gilles de Gennes pour la microfluidique

Abstract

We present the use of the synthetic clay fluorohectorite (Fh) as a drug delivery system of the antibiotic ciprofloxacin. The adsorption capacity is very high, and Fh promotes controlled drug release without changing drug effectiveness and toxicity.

Funder

Københavns Universitet

Danmarks Grundforskningsfond

Norges Forskningsråd

Norwegian Research Council

H2020 Marie Skłodowska-Curie Actions

Polish National Science Centre

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link