Alleviation of paraquat-induced oxidative lung injury by betaineviaregulation of sulfur-containing amino acid metabolism despite the lack of betaine-homocysteine methyltransferase (BHMT) in the lung-Reference-Cited by-同舟云学术

Alleviation of paraquat-induced oxidative lung injury by betaineviaregulation of sulfur-containing amino acid metabolism despite the lack of betaine-homocysteine methyltransferase (BHMT) in the lung

Published:2019 Issue:2 Volume:10 Page:1225-1234
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Na Jong Deok¹²³⁴,Choi Yeo Jin¹²³⁴,Jun Doo Sung¹²³⁴,Kim Young Chul¹²³⁴⁵^ORCID

Affiliation:

1. College of Pharmacy

2. Seoul National University

3. Seoul 151-742

4. Korea

5. Research Institute of Pharmaceutical Sciences

Abstract

Betaine regulates sulfur-containing amino acid metabolism in the lung despite the lack of BHMT and increases pulmonary antioxidant capacity.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C8FO01457D

Reference49 articles.

1. Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue

2. Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice

3. Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice

4. Protective effect of betaine against galactosamine-induced acute liver injury in rats

5. Dietary Betaine Promotes Generation of Hepatic S-Adenosylmethionine and Protects the Liver from Ethanol-Induced Fatty Infiltration

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