Hypoglycemic effect of a novel polysaccharide from Lentinus edodes on STZ-induced diabetic mice via metabolomics study and Nrf2/HO-1 pathway

Author:

Gong Pin1,Wang Xiaojuan1ORCID,Liu Meng1,Wang Mengrao1,Wang Siyuan1,Guo Yuxi1,Chang Xiangna1,Yang Wenjuan1,Chen Xuefeng1,Chen Fuxin2

Affiliation:

1. School of Food and biotechnological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China

2. School of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an, 710054, China

Abstract

A novel polysaccharide, LNT-1, from Lentinus edodes may be a potential natural drug candidate for the prevention and treatment of diabetes by regulating the oxidative stress response.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Yulin Science and Technology Bureau

Shaanxi Administration of Traditional Chinese Medicine

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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