Urinary caffeine and its metabolites in association with advanced liver fibrosis and liver steatosis: a nationwide cross-sectional study

Author:

Dong Rui1,Zhang Ru2,Shen Chao3,Shen Ya4,Shen Zhengkai4,Tian Ting4,Wang Jie1ORCID

Affiliation:

1. Department of Fundamental and Community Nursing, School of Nursing, Nanjing Medical University, Nanjing, China

2. Jiangsu College of Nursing, School of Nursing and Midwifery, Huaian, China

3. Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China

4. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China

Abstract

Most individual urinary caffeine metabolites and the major metabolite mixture were inversely linked to the risk of advanced liver fibrosis with subgroup variations. Only 7-MX was consistently linked to a reduced risk of liver steatosis.

Funder

Six Talent Peaks Project in Jiangsu Province

“333 Project” of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

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