Chiral lithium amide mediated desymmetrization of 3-substituted cyclobutanone-Reference-Cited by-同舟云学术

Chiral lithium amide mediated desymmetrization of 3-substituted cyclobutanone

Published:2021 Issue:12 Volume:8 Page:2977-2980
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhong Changxu¹²³⁴⁵,Wang Shaowei¹²³⁴⁵,Lu Ping¹²³⁴⁵^ORCID

Affiliation:

1. Department of Research Center for Molecular Recognition and Synthesis

2. Department of Chemistry

3. Fudan University

4. Shanghai 200433

5. P. R. China

Abstract

A practical approach to access enantioenriched cyclobutenes was developed via a chiral lithium amide mediated deprotonation of 3-substituted cyclobutanones. Further elaborations led to stereoselective assembly of tricyclic skeletons.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00015B

Reference25 articles.

1. A. Harrison-Marchand and J.Maddaluno , in Lithium Compounds in Organic Synthesis: From Fundamentals to Applications , ed. R. Luisi and V. Capriati , Wiley-VCH , Weinheim , 2014 , pp. 297–328

2. Direct Asymmetric Alkylation of Ketones: Still Unconquered

3. Enantioselective deprotonation by chiral lithium amide bases: asymmetric synthesis of trimethylsilyl enol ethers from 4-alkylcyclohexanones

4. Asymmetric deprotonation of prochiral ketones using chiral lithium amide bases

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Quinquevalent phosphorus acids;Organophosphorus Chemistry;2024-02-21

2. Recent Advances in Asymmetric Synthesis of Chiral Cyclobutenes;ChemCatChem;2024-01-19

3. Introduction;Springer Theses;2024

4. Dancing on Ropes ‐ Enantioselective Functionalization of Preformed Four‐Membered Carbocycles;Chinese Journal of Chemistry;2022-03-14

5. Total Synthesis of (+)-Kingianin A by Enantioselective Cycloaddition of Strained Cyclobutenone;Synthesis;2022-02-08