Salts, solvates and hydrates of the multi-kinase inhibitor drug pazopanib with hydroxybenzoic acids-Reference-Cited by-同舟云学术

Salts, solvates and hydrates of the multi-kinase inhibitor drug pazopanib with hydroxybenzoic acids

Published:2021 Issue:35 Volume:23 Page:5994-6011
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Rai Sunil K.¹^ORCID,Baidya Debjani¹^ORCID,Nangia Ashwini K.¹²^ORCID

Affiliation:

1. Division of Organic Chemistry, CSIR – National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India

2. School of Chemistry, University of Hyderabad, Prof. C. R. Rao Road, Gachibowli, Central University P.O., Hyderabad 500 046, India

Abstract

Eight cocrystal-salts of the multi-kinase drug pazopanib with hydroxybenzoic acids are sustained by the strong, ionic aminopyridinium⋯carboxylate heterosynthon of N–H⋯O hydrogen bonds between the carboxylic acid donor and amino-pyrimidine acceptor.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CE/D1CE00785H

Reference64 articles.

1. Crystal Engineering: A Holistic View

2. Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates

3. Crystal Engineering: From Molecule to Crystal