RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification-Reference-Cited by-同舟云学术

RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification

Published:2017 Issue:8 Volume:8 Page:5692-5698
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ren Xiaojun¹²³⁴⁵,Deng Ruijie⁵⁶⁷⁸⁴,Wang Lida⁵⁶⁷⁸⁴,Zhang Kaixiang⁵⁶⁷⁸⁴,Li Jinghong⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Beijing Institute of Technology

3. Beijing 100081

4. China

5. Department of Chemistry

6. Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology

7. Tsinghua University

8. Beijing 100084

Abstract

We report a highly sensitive method for quantifying the splicing products in different steps, enabling us to analyze the splicing process and identify ASO inhibitors.

Funder

National Natural Science Foundation of China

Tsinghua University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01336A

Reference43 articles.

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