Horizontal black lipid bilayer membranes for studying pore-forming toxins
Author:
Affiliation:
1. Ulm University
2. Institute of Analytical and Bioanalytical Chemistry
3. 89081 Ulm
4. Germany
5. Ulm University Medical Center
6. Institute of Pharmacology and Toxicology
Abstract
The investigation of pore-forming proteins such as the toxin component C2IIa from the binary Clostridium botulinum type C2 toxin is of particular interest for pharmaceutical applications, e.g., such as drug delivery into cells.
Funder
Baden-Württemberg Stiftung
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/AY/C8AY01122B
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1. Internalization of biotinylated compounds into cancer cells is promoted by a molecular Trojan horse based upon core streptavidin and clostridial C2 toxin
2. LHRH-PE40 Fusion Protein Tethered Silica Nanorattles for Imaging-Guided Tumor-Specific Drug Delivery and Bimodal Therapy
3. Human toxin-based recombinant immunotoxins/chimeric proteins as a drug delivery system for targeted treatment of human diseases
4. Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
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