Colloidal hydroxyethyl starch for tumor-targeted platinum delivery-Reference-Cited by-同舟云学术

Colloidal hydroxyethyl starch for tumor-targeted platinum delivery

Published:2019 Issue:3 Volume:1 Page:1002-1012
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Xiao Chen¹²³⁴⁵,Hu Hang¹²³⁴⁵,Yang Hai¹²³⁴⁵,Li Si¹²³⁴⁵,Zhou Hui⁶²³⁴⁵,Ruan Jian⁷⁴⁵,Zhu Yuting⁷⁴⁵,Yang Xiangliang¹²³⁴⁵,Li Zifu¹²³⁴⁵^ORCID

Affiliation:

1. National Engineering Research Center for Nanomedicine

2. College of Life Science and Technology

3. Huazhong University of Science and Technology

4. Wuhan

5. China

6. Department of Nanomedicine and Biopharmaceutics

7. Wuhan HUST Life Science & Technology Co., Ltd

Abstract

Hydroxyethyl starch (HES) was directly conjugated with cis-platinum prodrugviaan ester bond and decorated with active targeting molecule, lactobionic acid (LA), to afford LA-HES-Pt, which contributes toward higherin vitroantitumor activity against hepatoma carcinoma cells, HepG-2, as compared to cis-platinum.

Funder

National Natural Science Foundation of China

Huazhong University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NA/C8NA00271A

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