Coumarin-3-formylpyrazoles as 3-carbon synthons in cyclocondensation for the synthesis of spiro-fused pentacyclic spirooxindoles-Reference-Cited by-同舟云学术

Coumarin-3-formylpyrazoles as 3-carbon synthons in cyclocondensation for the synthesis of spiro-fused pentacyclic spirooxindoles

Published:2020 Issue:5 Volume:18 Page:845-850
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lei Chuan-Wen¹²³⁴⁵,Zhang Chuan-Bao¹²³⁴⁵,Wang Zhen-Hua⁶⁷⁴⁵^ORCID,Xie Ke-Xin⁸³⁴⁵,Zhao Jian-Qiang⁶⁷⁴⁵^ORCID,Zhou Ming-Qiang¹²³⁴⁵,Zhang Xiao-Mei¹²³⁴⁵^ORCID,Xu Xiao-Ying¹²³⁴⁵,Yuan Wei-Cheng¹²³⁴⁵^ORCID

Affiliation:

1. National Engineering Research Center of Chiral Drugs

2. Chengdu Institute of Organic Chemistry

3. Chinese Academy of Sciences

4. Chengdu

5. China

6. Institute for Advanced Study

7. Chengdu University

8. Chengdu Institute of Biology

Abstract

A range of spiro-fused pentacyclic spirooxindoles were smoothly obtained by using coumarin-3-formylpyrazoles as 3-carbon synthons via a tandem esterification/intramolecular Michael addition process.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Sichuan Province Youth Science and Technology Innovation Team

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02434D

Reference100 articles.

1. Gelsemine: A Thought-Provoking Target for Total Synthesis