Functional movements of the GABA type A receptor-Reference-Cited by-同舟云学术

Functional movements of the GABA type A receptor

Published:2020 Issue:28 Volume:22 Page:16023-16031
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Várnai Csilla¹²³⁴^ORCID,Irwin B. W. J.⁵⁶⁷⁸⁴^ORCID,Payne M. C.⁵⁶⁷⁸⁴^ORCID,Csányi Gábor⁹⁷¹⁰⁴^ORCID,Chau P.-L.¹¹¹²¹³¹⁴¹⁵^ORCID

Affiliation:

1. Centre for Computational Biology

2. University of Birmingham

3. Birmingham

4. UK

5. Theory of Condensed Matter Group

6. Cavendish Laboratory, Department of Physics

7. University of Cambridge

8. Cambridge CB3 0HE

9. Department of Engineering

10. Cambridge CB2 1PZ

11. Bioinformatique Structurale

12. Institut Pasteur CNRS URA 3528

13. CB3I CNRS USR 3756

14. 75724 Paris

15. France

Abstract

We have performed a Monte Carlo simulation of the GABA type A receptor. We have analysed the configurations and developed a correlation tensor method to predict receptor gating.

Funder

Engineering and Physical Sciences Research Council

Agence Nationale de la Recherche

Science and Technology Facilities Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CP/D0CP01128B

Reference34 articles.

1. Quaternary Structure of the Native GABAA Receptor Determined by Electron Microscopic Image Analysis

2. Structure, Function, and Modulation of GABAA Receptors

3. GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery?

4. Stoichiometry of a Ligand-gated Ion Channel Determined by Fluorescence Energy Transfer

5. Crystal structure of a human GABAA receptor

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