AlCl<sub>3</sub>-catalyzed regioselective intermolecular α or γ mono- or α,γ bis-hydroalkoxylation of allenamides with alcohols-Reference-Cited by-同舟云学术

AlCl₃-catalyzed regioselective intermolecular α or γ mono- or α,γ bis-hydroalkoxylation of allenamides with alcohols

Published:2022 Issue:23 Volume:20 Page:4719-4723
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Alam Khyarul¹^ORCID,Li Tian¹^ORCID,Hyatt I. F. Dempsey²^ORCID,Croatt Mitchell P.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, 435 Sullivan Science Building, Greensboro, North Carolina 27402, USA

2. Department of Chemistry and Biochemistry, Adelphi University, 1 South Ave., Garden City, New York, 11530, USA

Abstract

Simple conditions using AlCl3 for the regioselective intermolecular mono- or bis-hydroalkoxylation of allenamides are presented. The reactions showed good functional group tolerance and an initial mechanistic analysis is presented.

Funder

University of North Carolina at Greensboro

Adelphi University

American Chemical Society Petroleum Research Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00844K

Reference37 articles.

1. V. P.Ananikov and M.Tanaka , Hydrofunctionalization; Topics in Organometallic Chemistry , Springer , 2013 , vol 43