Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain-Reference-Cited by-同舟云学术

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Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain

Published:2016 Issue:5 Volume:1 Page:407-414
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Joo Jinmyoung¹²³⁴^ORCID,Kwon Ester J.⁵⁶⁷⁴,Kang Jinyoung⁸²³⁴,Skalak Matthew⁵⁶⁷⁴,Anglin Emily J.¹²³⁴,Mann Aman P.⁹¹⁰³⁴,Ruoslahti Erkki⁹¹⁰³⁴¹¹,Bhatia Sangeeta N.⁵⁶⁷⁴¹²,Sailor Michael J.¹²³⁴⁸

Affiliation:

1. Department of Chemistry

2. University of California

3. La Jolla

4. USA

5. Harvard-MIT Division of Health Science and Technology

6. Massachusetts Institute of Technology

7. Cambridge

8. Department of Nanoengineering

9. Cancer Research Center

10. Sanford-Burnham-Prebys Medical Discovery Institute

11. Center for Nanomedicine and Department of Molecular

12. Department of Electrical Engineering and Computer Science

Abstract

A chemically targeted luminescent porous silicon–graphene oxide core–shell nanoparticle delivers siRNA for more effective gene silencing.

Funder

Defense Advanced Research Projects Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NH/C6NH00082G

Reference60 articles.

1. Illuminating the silence: understanding the structure and function of small RNAs

2. Interfering with disease: a progress report on siRNA-based therapeutics

3. Current prospects for RNA interference-based therapies

4. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

5. RNA interference in the clinic: challenges and future directions

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