Purmedermycins A and B, two novel medermycin derivatives from Streptomyces sp. SS17A-Reference-Cited by-同舟云学术

Purmedermycins A and B, two novel medermycin derivatives from Streptomyces sp. SS17A

Published:2019 Issue:3 Volume:6 Page:399-404
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhou Biao¹²³⁴⁵,Jiang Yong-Jun¹²³⁴⁵,Li Jia-Qi¹²³⁴⁵,Zhang Hao-Jian¹²³⁴⁵,Ding Wan-Jing¹²³⁴⁵,Ma Zhong-Jun¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Marine Biology

2. Ocean College

3. Zhejiang University

4. Zhoushan 316021

5. People's Republic of China

Abstract

Purmedermycin A (1) and purmedermycin B (2), which were isolated from Streptomyces sp. SS17A, feature a rearranged and reconstructed C/D/E ring formed by the fusion of a tryptophan unit and medermycin or menoxymycin B, respectively, making them the first of a new type of medermycin.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C8QO01205A

Reference12 articles.

1. A new antibiotic, medermycin.

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3. Production of new hybrid antibiotics, mederrhodins A and B, by a genetically engineered strain

4. Menoxymycins A and B, new antitumor antibiotics generating active oxygen in tumor cells.

5. MDN-0171, a new medermycin analogue from Streptomyces albolongus CA-186053

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