Formation of glutathionyl dinitrosyl iron complexes protects against iron genotoxicity
Author:
Affiliation:
1. The Institute of Nuclear Chemistry and Technology
2. 03-195 Warsaw
3. Poland
4. Faculty of Medicine
5. University of Information Technology and Management in Rzeszów
Abstract
Formation of glutathionyl nitrosyl complexes abolishes the in vitro genotoxic effect of iron ions alone and iron ions in the presence of a naturally abundant antioxidant, GSH.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT00927H
Reference103 articles.
1. Endothelium-derived relaxing factor is a nitrosyl iron complex with thiol ligands
2. Reversible inactivation of E. coli endonuclease III via modification of its [4Fe-4S] cluster by nitric oxide
3. The Specific Interaction of Dinitrosyl-Diglutathionyl-Iron Complex, a Natural NO Carrier, with the Glutathione Transferase Superfamily
4. Glutathione Transferase Superfamily Behaves Like Storage Proteins for Dinitrosyl-Diglutathionyl-Iron Complex in Heterogeneous Systems
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