Anthranilic amide and imidazobenzothiadiazole compounds disruptMycobacterium tuberculosismembrane potential-Reference-Cited by-同舟云学术

Anthranilic amide and imidazobenzothiadiazole compounds disruptMycobacterium tuberculosismembrane potential

Author:

Smith Jake¹²³⁴,Wescott Heather¹²³⁴,Early Julie¹²³⁴,Mullen Steven¹²³⁴,Guzman Junitta¹²³⁴,Odingo Joshua¹²³⁴,Lamar Jason⁵⁶⁷⁴,Parish Tanya¹²³⁴^ORCID

Affiliation:

1. TB Discovery Research

2. Infectious Disease Research Institute

3. Seattle

4. USA

5. Lilly Research Laboratories

6. Eli Lilly and Company

7. Indianapolis

Abstract

Compounds1and2disruptM. tuberculosismembrane potential and demonstrate bactericidal activity against non-replicatingM. tuberculosisin pH 4.5 buffer.

Funder

Eli Lilly and Company

Bill and Melinda Gates Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

Reference34 articles.

1. Global Tuberculosis Report 2018 , World Health Organization , 2018

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