Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells-Reference-Cited by-同舟云学术

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Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells

Published:2016 Issue:2 Volume:7 Page:1514-1520
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Arai Midori A.¹²³⁴,Ishikawa Naoki¹²³⁴,Tanaka Mitsuha¹²³⁴,Uemura Kenji¹²³⁴,Sugimitsu Noriko¹²³⁴,Suganami Akiko⁵²⁶⁴,Tamura Yutaka⁵²⁶⁴,Koyano Takashi⁷⁸⁴,Kowithayakorn Thaworn⁹¹⁰¹¹¹²,Ishibashi Masami¹²³⁴

Affiliation:

1. Graduate School of Pharmaceutical Sciences

2. Chiba University

3. Chiba 260-8675

4. Japan

5. Graduate School of Medicine

6. Chiba 260-8670

7. Temko Corporation

8. Tokyo 164-0012

9. Faculty of Agriculture

10. Khon Kaen University

11. Khon Kaen 40002

12. Thailand

Abstract

Hes1 dimer inhibitor, agalloside (2), which can accelerate the differentiation of neural stem cells was isolated by using Hes1-immobilized beads.

Funder

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science, and Technology

Uehara Memorial Foundation

Naito Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC03540F

Reference58 articles.

1. Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

2. Neurogenesis in the adult human hippocampus

3. Adult neurogenesis: From canaries to the clinic

4. Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

5. Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model

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