A tumor microenvironment (TME)-responsive nanoplatform for systemic saporin delivery and effective breast cancer therapy-Reference-Cited by-同舟云学术

A tumor microenvironment (TME)-responsive nanoplatform for systemic saporin delivery and effective breast cancer therapy

Published:2021 Issue:20 Volume:57 Page:2563-2566
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Shen Qian¹²³⁴,Xu Lei⁵⁶⁷⁸⁹,Li Rong¹²³⁴,Wu Guang¹²³⁴,Li Senlin⁵⁶⁷⁸⁹,Saw Phei Er⁵⁶⁷⁸⁹,Zhou Yusheng¹²³⁴¹⁰,Xu Xiaoding¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Pharmacy & Pharmacology and the Second Affiliated Hospital

2. University of South China

3. Hengyang 421001

4. P. R. China

5. Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation

6. Medical Research Center

7. Sun Yat-sen Memorial Hospital

8. Sun Yat-sen University

9. Guangzhou 510120

10. The Affiliated Nanhua Hospital

Abstract

A robust TME pH-responsive nanoplatform was herein developed. This nanoplatform could significantly improve intracellular delivery of cytotoxic saporin to achieve an effective inhibition of tumor growth of breast cancer.

Funder

Guangdong Science and Technology Department

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D0CC07808E

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