Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase-Reference-Cited by-同舟云学术

Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase

Published:2016 Issue:12 Volume:15 Page:1468-1475
ISSN:1474-905X
Container-title:Photochemical & Photobiological Sciences
language:en
Short-container-title:Photochem. Photobiol. Sci.

Author:

Abrahams Amaal¹²³⁴³,Mouchet Nicolas¹²³⁴³,Gouault Nicolas⁴³⁵⁶³,Lohézic Le Dévéhat Françoise⁴³⁵⁶³,Le Roch Myriam⁴³⁵⁶³,Rouaud Isabelle⁴³⁵⁶³,Gilot David¹²³⁴³,Galibert Marie-Dominique¹²³⁴³

Affiliation:

1. CNRS UMR6290

2. Institut de Génétique et Développement de Rennes

3. France

4. University of Rennes1

5. CNRS UMR6226

6. Sciences Chimiques de Rennes

Abstract

Identification and validation of the pyrrole-2 derivative using a gene expression approach on relevant p38 target genes in cellular and skin explant systems.

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/PP/C6PP00283H

Reference31 articles.

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3. Keratinocytes as initiators of inflammation

4. The UV response of the skin: a review of the MAPK, NFκB and TNFα signal transduction pathways

5. N. Mouchet , H.Adamski, R.Bouvet, S.Corre, Y.Courbebaisse and E.Watier, et al., In vivo identification of solar radiation-responsive gene network: role of the p38 stress-dependent kinase, 2010

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