Model peptides containing the 3-sulfanyl-norbornene amino acid, a conformationally constrained cysteine analogue effective inducer of 310-helix secondary structures-Reference-Cited by-同舟云学术

Model peptides containing the 3-sulfanyl-norbornene amino acid, a conformationally constrained cysteine analogue effective inducer of 310-helix secondary structures

Published:2015 Issue:41 Volume:5 Page:32643-32656
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ruffoni Alessandro¹²³⁴⁵,Contini Alessandro¹²³⁴⁵,Soave Raffaella⁶⁴⁵,Lo Presti Leonardo¹⁷⁴⁵,Esposto Irene¹²³⁴⁵,Maffucci Irene¹²³⁴⁵,Nava Donatella¹²³⁴⁵,Pellegrino Sara¹²³⁴⁵,Gelmi Maria Luisa¹²³⁴⁵,Clerici Francesca¹²³⁴⁵

Affiliation:

1. Università degli Studi di Milano

2. Dipartimento di Scienze Farmaceutiche

3. Sezione di Chimica Generale e Organica “Alessandro Marchesini”

4. 20133 Milano

5. Italy

6. CNR-Istituto di Scienze e Tecnologie Molecolari

7. Dipartimento di Chimica

Abstract

Two model peptides containing the 3-benzylsulfanylnorbornene amino acid (NRB) was prepared. Theoretical calculations, spectroscopic and X-ray analyses confirmed that both NRB enantiomers possess a strong right-handed helicogenic effect.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA03805G

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